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Stk38 protein kinase preferentially inhibits TLR9-activated inflammatory responses by promoting MEKK2 ubiquitination in macrophages.
Wen M, Ma X, Cheng H, Jiang W, Xu X, Zhang Y, Zhang Y, Guo Z, Yu Y, Xu H, Qian C, Cao X, An H. Wen M, et al. Nat Commun. 2015 May 18;6:7167. doi: 10.1038/ncomms8167. Nat Commun. 2015. PMID: 25981615 Free article.
Stk38 constitutively associates with ubiquitin E3 ligase Smurf1, and facilitates Smurf1-mediated MEKK2 ubiquitination and degradation. ...Stk38-deficient mice are also more susceptible to CLP-induced sepsis than control mice. ...
Stk38 constitutively associates with ubiquitin E3 ligase Smurf1, and facilitates Smurf1-mediated MEKK2 ubiquitination and degradation …
NDR1/STK38 potentiates NF-kappaB activation by its kinase activity.
Shi DD, Shi H, Lu D, Li R, Zhang Y, Zhang J. Shi DD, et al. Cell Biochem Funct. 2012 Dec;30(8):664-70. doi: 10.1002/cbf.2846. Epub 2012 Jun 4. Cell Biochem Funct. 2012. PMID: 22674419
Human NDR1/STK38 belongs to the nuclear-Dbf2-related (NDR) family of Ser/Thr kinases. ...
Human NDR1/STK38 belongs to the nuclear-Dbf2-related (NDR) family of Ser/Thr kinases. ...
Analysis of gene expression in ductal carcinoma in situ of the breast.
Adeyinka A, Emberley E, Niu Y, Snell L, Murphy LC, Sowter H, Wykoff CC, Harris AL, Watson PH. Adeyinka A, et al. Clin Cancer Res. 2002 Dec;8(12):3788-95. Clin Cancer Res. 2002. PMID: 12473591
EXPERIMENTAL DESIGN: We have compared gene expression within a cohort of six cases of DCIS with necrosis (DCIS(necrosis+)) and four cases without necrosis (DCIS(necrosis-)) using microdissection and cDNA microarray. ...Further study of angio-associated …
EXPERIMENTAL DESIGN: We have compared gene expression within a cohort of six cases of DCIS with necrosis (DCIS(necrosis+)) and …